Technology
Comprehensive software and processes covering the entire plasmid life cycle, from design to distribution.
Trusted and validated by the scientific community.
Design
Our plasmid design technology combines cutting-edge software, proprietary design rules, and curated libraries of genetic components to streamline the creation of plasmids customized to meet your project's unique goals. By integrating advanced algorithms with decades of genetic engineering expertise, we ensure every design is optimized for functionality, manufacturability, and regulatory compliance. Our modular libraries of genetic components enable rapid customization, empowering researchers to unlock new possibilities in basic research and product development.
Biobanking
GenoFAB leverages cutting-edge inventory management technologies to track plasmids at every stage of their lifecycle. Our proprietary laboratory information management system (LIMS) ensures precise oversight, while advanced label printing and barcoding streamline sample identification and handling. This integrated approach guarantees traceability, accuracy, and efficiency throughout the plasmid management process. This innovative system supports all plasmid management processes, ensuring seamless operations and allowing you to focus on advancing your research.
Assembly
GenoFAB uses bioinformatics and optimization algorithms to maximize the reuse of existing genetic material, minimizing the need for slow and expensive de novo synthesis. Unlike traditional methods, we don’t rely on restriction enzymes or existing expression vectors, giving us complete flexibility to design and produce any plasmids our clients need. By retaining all plasmids we produce, we maintain a robust repository of reusable materials, enabling faster, more cost-effective, and fully customizable plasmid solutions.
Security
GenoFAB has developed a patented technology leveraging advanced cryptographic and data encoding algorithms to secure plasmid exchanges. By embedding digital certificates directly into plasmid sequences, we allow plasmid users to quickly verify their authenticity and integrity even without access to sensitive documentation. Our technology offers a reliable solution for protecting intellectual property and maintaining trust in collaborative projects, reducing technical and legal risks for researchers and organizations alike.
Validation
Funded by NSF and NIH
GenoFAB's technology was developed with funding from the National Science Foundation and the National Institutes of Health.
- NIH R01GM147816: Development
of a technology to certify engineered DNA molecules - NSF 1241328: INSPIRE: Modeling and optimization of DNA manufacturing processes
- NSF 0850100: GenoCAD: A Computer Assisted Design Environment for Synthetic Biology
Published in high-impact journals
Technologies were first described in peer-reviewed publications that have received thousands of citations.
- Writing DNA with GenoCAD (2009) Nucleic Acids Research https://doi.org/10.1093/nar/gkp361
- GenoLIB: a database of biological parts derived from a library of common plasmid features (2015) Nucleic Acids Research https://doi.org/10.1093/nar/gkv272
- Opportunities to apply manufacturing systems analysis techniques in genetic manufacturing systems (2017) Manufacturing
letters https://doi.org/10.1016/j.mfglet.2017.06.003 - Securing the Exchange of Synthetic Genetic Constructs Using Digital Signatures (2020) ACS Synthetic Biology https://doi.org/10.1021/acssynbio.0c00401
- Sequencing strategies to ensure accurate plasmid assembly (2024) ACS
Synthetic Biology https://doi.org/10.1021/acssynbio.4c00539
Curious?
Schedule a call today to discuss how you can evaluate our technology with a pilot project!